UConn vs. Louisville Women's Basketball Predictions - Nov. 4

Grambling State v Louisville

Photo: Andy Lyons / Getty Images Sport / Getty Images

The UConn Huskies hit the court against the Louisville Cardinals on November 4, 2025 ET in the opening contest of the 2025-26 season for both teams.

Tuesday's matchup between the Huskies and the Cardinals sees the Huskies as an enormous, 24.5-point favorite. The over/under is 136.5 points for the game.

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UConn vs. Louisville Odds and Game Info

  • Game day: Tuesday, November 4, 2025
  • Game time: 5:30 p.m. ET
  • TV channel: ESPN
  • Location: Annapolis, Maryland
  • Arena: Navy Alumni Hall

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UConn vs. Louisville Odds and Prediction

  • Spread favorite: UConn (-24.5)
  • Moneyline: UConn (-10000), Louisville (+3000)
  • Total: 136.5 points

Pick ATS:Louisville (+24.5)

  • Pick OU: Over (136.5)
  • Prediction: UConn 79, Louisville 57

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UConn vs. Louisville Comparison (2024-25 Stats)

UConn Rank UConn Stat Louisville Stat Louisville Rank
9th 81.7 Points Scored 71.8 75th
1st 52.2 Points Allowed 67.5 248th
3rd 20.8 Assists 14.5 87th
3rd 10.2 Turnovers 14.8 147th
1st 50.9% Field Goal % 42.6% 109th
4th 34.7% Field Goal % Allowed 44.6% 351st

UConn 2024-25 Key Players

  • Paige Bueckers scored 19.9 points per game last season along with 4.6 assists.
  • Sarah Strong averaged 8.9 boards per game in addition to a PPG average of 16.4.
  • Azzi Fudd knocked down 2.3 threes per game a season ago.
  • Strong was a standout on the defensive end last season, collecting 2.3 steals and 1.7 blocks per contest.

Louisville 2024-25 Key Players

  • Jayda Curry scored 14.4 points and distributed 3.3 assists per game last season.
  • Olivia Cochran averaged 6.7 boards per game in addition to a PPG average of 10.4.
  • Curry hit an average of 2.1 shots per game from beyond the arc a season ago.
  • Tajianna Roberts and Cochran were defensive standouts last season, with Roberts averaging 1.7 steals per game and Cochran collecting 0.4 blocks per contest.

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